2019 News:

School of Brain Cells & Circuits

“Camillo Golgi”

Ettore Majorana Foundation and Centre for Scientific Culture, Erice (Italy)

Modeling the brain and its pathologies

Course Directors: Egidio D’Angelo, Claudia Gandini Wheeler-Kingshott & Viktor Jirsa

Date: 27th August – 1st September 2019

Abstract submission is now open.



Casella Prize 2019 awarded  to Idan Segev


The Casella Prize 2019 is awarded to Prof. Idan Segev for his outstanding scientific activity in neuroscience, with specific regard to brain modeling. Especially relevant are the results, published in top-rank international journals, on the biophysical and mathematical structure of neuronal and microcircuit functions of the cerebral cortex in mouse and humans. These results open important scenarios for future neuroscientific studies and suggest potential applications in the biomedical sector.

The video of the talk can be found at this link: Brain in the computer: what did I learn from simulating the brain




The Brain Simulation platform just tweeted:






CASELLA PRIZE, 22 May 2019

L E C T I O     M A G I S T R A L I S



Brain in the computer:

what did I learn from simulating the brain

Prof. Idan Segev


Department of Neurobiology and the Edmond and Lily Safra Center for Brain Sciences Hebrew University of Jerusalem

Jerusalem, Israel

Almo Collegio Borromeo | Piazza Collegio Borromeo 9, Pavia | www.collegioborromeo.it | eventi@collegioborromeo.it


More info will come soon



Front. Neuroinform. | doi: 10.3389/fninf.2019.00037




New neuronal model with potential to tackle spinocerebellar ataxias disease




Articolo di E. D’Angelo su “Science”: Il cervelletto diventa sociale!

Courses for PhD Students

  • Fundamentals of Data Analysis,

Dr Thierry Nieus  8, 15 e 22 march 2019 h 11-13
aula A di Fisiologia Umana, in via Forlanini 6, Dip. di Medicina Molecolare

  • Dynamical systems, complexity and consciousness, Dr Cattani 17 e il 31 may  h 10-13 Aula da definirsi.

On BioRxiv the scaffold model of the cerebellar network:


The cerebellum gets social

Egidio D’Angelo

Science  18 Jan 2019:
Vol. 363, Issue 6424, pp. 229
DOI: 10.1126/science.aaw2571


Cereb Cortex. 2019 Jan 7. doi: 10.1093/cercor/bhy322.
I See Your Effort: Force-Related BOLD Effects in an Extended Action Execution-Observation Network Involving the Cerebellum.
Casiraghi L, Alahmadi AAS, Monteverdi A, Palesi F, Castellazzi G, Savini G, Friston K, Gandini Wheeler-Kingshott CAM, D’Angelo E.

Action observation (AO) is crucial for motor planning, imitation learning, and social interaction, but it is not clear whether and how an action execution-observation network (AEON) processes the effort of others engaged in performing actions. In this functional magnetic resonance imaging (fMRI) study, we used a “squeeze ball” task involving different grip forces to investigate whether AEON activation showed similar patterns when executing the task or observing others performing it. Both in action execution, AE (subjects performed the visuomotor task) and action observation, AO (subjects watched a video of the task being performed by someone else), the fMRI signal was detected in cerebral and cerebellar regions. These responses showed various relationships with force mapping onto specific areas of the sensorimotor and cognitive systems. Conjunction analysis of AE and AO was repeated for the “0th” order and linear and nonlinear responses, and revealed multiple AEON nodes remapping the detection of actions, and also effort, of another person onto the observer’s own cerebrocerebellar system. This result implies that the AEON exploits the cerebellum, which is known to process sensorimotor predictions and simulations, performing an internal assessment of forces and integrating information into high-level schemes, providing a crucial substrate for action imitation.

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