School of Brain Cells & Circuits
Modeling the brain and its pathologies
Course Directors: Egidio D’Angelo, Claudia Gandini Wheeler-Kingshott & Viktor Jirsa
Date: 27th August – 1st September 2019
Abstract submission is now open.
Casella Prize 2019 awarded to Idan Segev
The Casella Prize 2019 is awarded to Prof. Idan Segev for his outstanding scientific activity in neuroscience, with specific regard to brain modeling. Especially relevant are the results, published in top-rank international journals, on the biophysical and mathematical structure of neuronal and microcircuit functions of the cerebral cortex in mouse and humans. These results open important scenarios for future neuroscientific studies and suggest potential applications in the biomedical sector.
The video of the talk can be found at this link: Brain in the computer: what did I learn from simulating the brain
The Brain Simulation platform just tweeted:
Congratulations to our collaborator @Segev_Lab who has been awarded the Casella Prize by the Almo Collegio Borromeo of Pavia. If you are in Pavia, Italy the lecture ‘Brain in the computer’ will take place at 21:00 CEST on Wed 22 May @HumanBrainProj @egidio_dangelo pic.twitter.com/c2SEnUoL2a
— HBP Brain Simulation (@HBPBrainSim) 14 maggio 2019
CASELLA PRIZE, 22 May 2019
L E C T I O M A G I S T R A L I S
Brain in the computer:
what did I learn from simulating the brain
Department of Neurobiology and the Edmond and Lily Safra Center for Brain Sciences Hebrew University of Jerusalem
More info will come soon
Courses for PhD Students
- Fundamentals of Data Analysis,
Dr Thierry Nieus 8, 15 e 22 march 2019 h 11-13
aula A di Fisiologia Umana, in via Forlanini 6, Dip. di Medicina Molecolare
- Dynamical systems, complexity and consciousness, Dr Cattani 17 e il 31 may h 10-13 Aula da definirsi.
On BioRxiv the scaffold model of the cerebellar network:
The cerebellum gets social
Science 18 Jan 2019:
Vol. 363, Issue 6424, pp. 229
Cereb Cortex. 2019 Jan 7. doi: 10.1093/cercor/bhy322.
I See Your Effort: Force-Related BOLD Effects in an Extended Action Execution-Observation Network Involving the Cerebellum.
Casiraghi L, Alahmadi AAS, Monteverdi A, Palesi F, Castellazzi G, Savini G, Friston K, Gandini Wheeler-Kingshott CAM, D’Angelo E.
Action observation (AO) is crucial for motor planning, imitation learning, and social interaction, but it is not clear whether and how an action execution-observation network (AEON) processes the effort of others engaged in performing actions. In this functional magnetic resonance imaging (fMRI) study, we used a “squeeze ball” task involving different grip forces to investigate whether AEON activation showed similar patterns when executing the task or observing others performing it. Both in action execution, AE (subjects performed the visuomotor task) and action observation, AO (subjects watched a video of the task being performed by someone else), the fMRI signal was detected in cerebral and cerebellar regions. These responses showed various relationships with force mapping onto specific areas of the sensorimotor and cognitive systems. Conjunction analysis of AE and AO was repeated for the “0th” order and linear and nonlinear responses, and revealed multiple AEON nodes remapping the detection of actions, and also effort, of another person onto the observer’s own cerebrocerebellar system. This result implies that the AEON exploits the cerebellum, which is known to process sensorimotor predictions and simulations, performing an internal assessment of forces and integrating information into high-level schemes, providing a crucial substrate for action imitation.